Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF123RING-type domain-containing protein. (667 aa)    
Predicted Functional Partners:
UBAC1
UBA domain containing 1.
   
 
 0.964
LOC102353140
Ring finger protein 123.
 
     0.947
USP19
Ubiquitin specific peptidase 19.
   
 0.820
CNNM3
Cyclin and CBS domain divalent metal cation transport mediator 3.
      
 0.744
USP48
Ubiquitin specific peptidase 48; Belongs to the peptidase C19 family.
    
   0.714
USP11
Ubiquitin specific peptidase 11.
   
 0.706
APEH
Acylaminoacyl-peptide hydrolase.
   
  
 0.649
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 
 0.618
NFKB1
Nuclear factor kappa B subunit 1.
    
   0.612
NFKB2
Nuclear factor kappa B subunit 2.
    
   0.612
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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