STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCM2CCM2 scaffold protein. (447 aa)    
Predicted Functional Partners:
KRIT1
KRIT1 ankyrin repeat containing.
    
 0.999
PDCD10
Programmed cell death 10.
    
 0.999
ITGB1BP1
Integrin subunit beta 1 binding protein 1.
    
 
 0.992
SMURF2
E3 ubiquitin-protein ligase.
    
 0.967
MAP3K3
Mitogen-activated protein kinase kinase kinase 3.
    
 0.939
LOC102350357
Uncharacterized protein.
    
 0.939
CTNNB1
Catenin beta 1.
    
 0.915
SMURF1
SMAD specific E3 ubiquitin protein ligase 1.
    
  0.908
MTMR9
Myotubularin related protein 9.
   
 
 0.846
EFCAB2
EF-hand calcium binding domain 2.
    
 0.839
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.