STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (835 aa)    
Predicted Functional Partners:
PIGW
Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
     
 0.922
CRTAC1
Cartilage acidic protein 1.
      
 0.860
ITGB8
Integrin beta; Belongs to the integrin beta chain family.
    
 0.656
TGFB1
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.524
ALDH5A1
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
      
 0.516
CD109
CD109 molecule.
   
  0.495
VCL
Vinculin.
   
 0.494
THY1
Thy-1 cell surface antigen.
   
 
 0.481
ITGB6
Integrin beta; Belongs to the integrin beta chain family.
   
 0.476
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.476
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.