Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (835 aa)    
Predicted Functional Partners:
PIGW
Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
     
 0.937
PIGL
Phosphatidylinositol glycan anchor biosynthesis class L.
     
 0.916
CRTAC1
Cartilage acidic protein 1.
    
 
 0.849
SERPIND1
Serpin family D member 1; Belongs to the serpin family.
   
 
 0.622
PIGN
Phosphatidylinositol glycan anchor biosynthesis class N.
     
 0.610
MANF
Mesencephalic astrocyte derived neurotrophic factor.
      
 0.600
FUCA2
Alpha-L-fucosidase 2.
      
 0.594
PLPP3
Phospholipid phosphatase 3.
    
 
 0.591
PLPP2
Phospholipid phosphatase 2.
      
 0.587
PLPP1
Phospholipid phosphatase 1.
      
 0.547
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.