Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC102357296FPL domain-containing protein. (365 aa)    
Predicted Functional Partners:
CLEC16A
C-type lectin domain containing 16A.
 
      0.900
GPN1
GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
 
  
   0.889
TFB1M
rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
 
  
   0.870
PTPN22
Protein tyrosine phosphatase non-receptor type 22.
      
 0.796
RNF41
Ring finger protein 41.
    
 
 0.779
SH2B3
SH2B adaptor protein 3.
      
 0.738
BACH2
BTB domain and CNC homolog 2.
      
 0.725
ERBB3
Protein kinase domain-containing protein.
      
 0.653
VPS26B
VPS26, retromer complex component B.
    
 
 0.646
DEXI
Dexi homolog.
      
 0.606
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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