Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ULK3Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (471 aa)    
Predicted Functional Partners:
SUFU
SUFU negative regulator of hedgehog signaling.
     
 0.944
GLI1
GLI family zinc finger 1.
    
 0.908
GLI2
GLI family zinc finger 2.
    
 0.898
ULK2
Unc-51 like autophagy activating kinase 2.
    
 
 0.868
IST1
IST1 factor associated with ESCRT-III.
    
 
 0.854
ULK1
Unc-51 like autophagy activating kinase 1.
    
 
 0.819
ATG101
Autophagy related 101.
    
 0.818
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.817
BECN1
Beclin 1, autophagy related.
    
 0.815
PIK3R4
Phosphoinositide-3-kinase regulatory subunit 4.
    
 0.815
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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