STRINGSTRING
DRD5 protein (Latimeria chalumnae) - STRING interaction network
"DRD5" - Dopamine receptor D5 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DRD5Dopamine receptor D5 (460 aa)    
Predicted Functional Partners:
GNAL
Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (379 aa)
     
  0.898
GNAS
GNAS complex locus (377 aa)
     
  0.898
GNG2
Guanine nucleotide binding protein (G protein), gamma 2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (71 aa)
       
  0.605
ADCY6
Adenylate cyclase 6 (894 aa)
     
 
  0.588
ADCY5
Adenylate cyclase 5 (824 aa)
     
 
  0.588
POMC
Proopiomelanocortin (255 aa)
     
  0.581
MC4R
Melanocortin 4 receptor (329 aa)
         
0.580
ADORA2A
Adenosine A2a receptor; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (445 aa)
     
 
0.570
ADORA2B
Adenosine A2b receptor (325 aa)
     
 
0.566
AVPR2
Arginine vasopressin receptor 2 (365 aa)
     
 
  0.561
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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