STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRB10Growth factor receptor bound protein 10. (433 aa)    
Predicted Functional Partners:
FGR
Tyrosine-protein kinase.
   
 0.735
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.700
LCK
Tyrosine-protein kinase.
   
 0.623
LOC102348007
Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).
    
  0.611
GRB2
Growth factor receptor bound protein 2.
    
0.606
RET
Ret proto-oncogene; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.589
H3ACE0_LATCH
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.568
FYN
Tyrosine-protein kinase.
   
 0.555
WDR90
WD repeat domain 90.
    
  0.553
TEK
TEK receptor tyrosine kinase.
   
 0.553
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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