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GRB10 protein (Latimeria chalumnae) - STRING interaction network
"GRB10" - Growth factor receptor-bound protein 10 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRB10Growth factor receptor-bound protein 10 (433 aa)    
Predicted Functional Partners:
IGF1R
Insulin-like growth factor 1 receptor (1170 aa)
       
  0.898
INSR
Insulin receptor (838 aa)
       
  0.898
ENSLACG00000009952
Insulin receptor (270 aa)
       
  0.862
ENSLACG00000015295
Uncharacterized protein (954 aa)
       
  0.514
RET
Ret proto-oncogene (1090 aa)
       
  0.500
ENSLACG00000006484
Uncharacterized protein ; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (111 aa)
         
  0.500
TEK
TEK tyrosine kinase, endothelial (914 aa)
       
  0.494
TIE1
Tyrosine kinase with immunoglobulin-like and EGF-like domains 1 (1143 aa)
       
  0.494
IRS2
Insulin receptor substrate 2 (1069 aa)
       
  0.481
IRS1
Insulin receptor substrate 1 (1076 aa)
       
  0.481
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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