Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GRB10Growth factor receptor bound protein 10. (433 aa)    
Predicted Functional Partners:
IGF1R
Insulin like growth factor 1 receptor.
    
 0.963
H3B8U3_LATCH
Serine/threonine-protein kinase TOR.
    
 0.906
RET
Ret proto-oncogene; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.790
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.775
TEK
TEK receptor tyrosine kinase.
    
  0.704
LOC102348007
Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).
    
  0.666
LOC102358202
Tyrosine-protein kinase receptor.
    
 0.654
INSR
Uncharacterized protein.
    
 0.654
H3B644_LATCH
Uncharacterized protein.
    
 0.654
INSRR
Tyrosine-protein kinase receptor.
    
 0.654
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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