Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRP8LDL receptor related protein 8. (842 aa)    
Predicted Functional Partners:
PCSK9
Proprotein convertase subtilisin/kexin type 9.
    
 0.929
DAB1
DAB adaptor protein 1.
    
 0.925
RELN
Reelin.
    
 0.922
MYLIP
Myosin regulatory light chain interacting protein.
    
 0.890
APOB
Apolipoprotein B.
    
 0.888
LDLRAP1
Low density lipoprotein receptor adaptor protein 1b.
    
 0.823
SRMS
Tyrosine-protein kinase.
    
 0.625
FYN
Tyrosine-protein kinase.
    
 0.625
FGR
Tyrosine-protein kinase.
    
 0.625
AXIN1
Axin 1.
    
 0.595
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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