STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRP8LDL receptor related protein 8. (842 aa)    
Predicted Functional Partners:
RELN
Reelin.
    
 0.864
PCSK9
Proprotein convertase subtilisin/kexin type 9.
    
 0.847
DAB1
DAB adaptor protein 1.
    
 0.832
LDLRAP1
Low density lipoprotein receptor adaptor protein 1b.
    
 0.749
F11
Coagulation factor XI; Belongs to the peptidase S1 family.
    
 
 0.747
APOB
Apolipoprotein B.
    
 0.674
ITSN2
Intersectin 2.
    
 0.656
MYLIP
Myosin regulatory light chain interacting protein.
    
 0.593
LOC102358266
Dickkopf WNT signaling pathway inhibitor 1b.
    
 0.550
KREMEN1
Kringle containing transmembrane protein 1.
    
 0.539
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.