Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H2ZX25_LATCHANK_REP_REGION domain-containing protein. (269 aa)    
Predicted Functional Partners:
BLOC1S6
Biogenesis of lysosomal organelles complex 1 subunit 6.
    
 0.769
SH3YL1
SH3 and SYLF domain containing 1.
    
 
 0.727
H3B2B0_LATCH
SH3 domain-containing protein.
     
 0.651
NEBL
Nebulette.
    
 
 0.642
ARHGAP26
Rho GTPase activating protein 26.
    
 
 0.641
SNX18
Sorting nexin.
    
 0.631
LIAS
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
      
 0.614
BLK
Tyrosine-protein kinase.
    
 0.607
GPSM1
G protein signaling modulator 1.
    
 
 0.602
RRAD
RRAD, Ras related glycolysis inhibitor and calcium channel regulator.
    
 0.598
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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