STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNAJC13DnaJ heat shock protein family (Hsp40) member C13. (2247 aa)    
Predicted Functional Partners:
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6.
   
  
 0.876
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.835
GAK
J domain-containing protein.
   
  
 0.732
VPS13C
Vacuolar protein sorting 13 homolog C.
   
  
 0.722
RIC3
RIC3 acetylcholine receptor chaperone.
      
 0.708
SYNJ1
Synaptojanin 1.
   
  
 0.706
HTRA2
HtrA serine peptidase 2.
      
 0.699
ATXN2
Ataxin 2.
   
  
 0.692
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
      
 0.686
SPG11
SPG11 vesicle trafficking associated, spatacsin.
   
  
 0.672
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.