Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PATJPATJ crumbs cell polarity complex component. (2073 aa)    
Predicted Functional Partners:
MPP5
Membrane palmitoylated protein 5; Belongs to the MAGUK family.
   
 0.948
HTR2C
5-hydroxytryptamine receptor 2C; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.726
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.653
KANK4
KN motif and ankyrin repeat domains 4.
    
 0.637
ANKLE2
Ankyrin repeat and LEM domain containing 2.
    
 
 0.636
MPP7
Membrane palmitoylated protein 7; Belongs to the MAGUK family.
   
 0.619
MPP3
Membrane palmitoylated protein 3; Belongs to the MAGUK family.
   
 0.619
AMOTL1
Angiomotin like 1.
    
 
 0.608
AMOT
Angiomotin.
    
 
 0.608
PARD6A
Par-6 family cell polarity regulator alpha.
    
 0.593
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (16%) [HD]