STRINGSTRING
ENSLACG00000001779 protein (Latimeria chalumnae) - STRING interaction network
"ENSLACG00000001779" - Uncharacterized protein in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSLACG00000001779Uncharacterized protein (327 aa)    
Predicted Functional Partners:
TP53
Tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (401 aa)
     
  0.715
CENPI
Centromere protein I (701 aa)
     
 
  0.626
TRIP12
Thyroid hormone receptor interactor 12 (2023 aa)
     
 
  0.617
PRAM1
PML-RARA regulated adaptor molecule 1 (220 aa)
           
  0.587
PLK2
Polo-like kinase 2 (731 aa)
     
  0.586
PLK1
Polo-like kinase 1 (595 aa)
     
  0.582
OIP5
Opa interacting protein 5 (257 aa)
     
 
  0.569
MIS18BP1
MIS18 binding protein 1 (745 aa)
         
  0.544
TFAP2A
Transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (438 aa)
       
    0.538
NAP1L4
Nucleosome assembly protein 1-like 4 (410 aa)
     
      0.518
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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