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TRIM24 protein (Latimeria chalumnae) - STRING interaction network
"TRIM24" - Tripartite motif containing 24 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRIM24Tripartite motif containing 24 (473 aa)    
Predicted Functional Partners:
TAF12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa (217 aa)
     
  0.717
TAF7
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa (366 aa)
     
  0.716
TAF2
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa (1039 aa)
     
  0.715
TADA3
Transcriptional adaptor 3 (312 aa)
     
  0.705
TAF5L
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa (564 aa)
     
  0.703
TAF5
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa (622 aa)
     
  0.703
TAF6L
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa (657 aa)
     
  0.701
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa (675 aa)
     
  0.701
TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa (142 aa)
     
  0.695
TP53
Tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (401 aa)
       
  0.686
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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