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STRINGSTRING
ENSLACG00000001792 protein (Latimeria chalumnae) - STRING interaction network
"ENSLACG00000001792" - Uncharacterized protein in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSLACG00000001792Uncharacterized protein; mutS homolog 2 (E. coli) (360 aa)    
Predicted Functional Partners:
MSH6
MutS homolog 6; Component of the post-replicative DNA mismatch repair system (MMR) (1361 aa)
     
 
0.965
POLE
Polymerase (DNA directed), epsilon, catalytic subunit (2289 aa)
     
 
  0.941
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (260 aa)
     
 
  0.937
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] (317 aa)
   
 
  0.928
POLD1
Polymerase (DNA directed), delta 1, catalytic subunit (1103 aa)
     
 
  0.928
MSH2
Uncharacterized protein; mutS homolog 2 (447 aa)
 
     
    0.926
EXO1
Exonuclease 1 (805 aa)
   
 
  0.921
MSH3
MutS homolog 3; Component of the post-replicative DNA mismatch repair system (MMR) (798 aa)
     
 
0.900
MLH1
mutL homolog 1 (821 aa)
   
 
  0.884
PMS2
PMS1 homolog 2, mismatch repair system component; PMS2 postmeiotic segregation increased 2 (S. cerevisiae) (872 aa)
   
 
  0.883
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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