Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2ZX87_LATCHTcp10_C domain-containing protein. (180 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.957
PLK4
Polo like kinase 4.
   
 0.921
STIL
STIL centriolar assembly protein.
   
 
 0.902
CENPJ
Uncharacterized protein.
 
      0.900
H3AJ45_LATCH
Uncharacterized protein.
    
 0.892
ITSN1
Intersectin 1 (SH3 domain protein).
    
 0.892
TUBG1
Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.
    
 
 0.869
PLK1
Serine/threonine-protein kinase PLK.
   
 0.857
H2ZWA0_LATCH
Uncharacterized protein.
   
 
 0.848
SASS6
SAS-6 centriolar assembly protein.
   
 
 0.848
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.