Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H2ZX94_LATCHDehydrogenase/reductase (SDR family) member 12. (325 aa)    
Predicted Functional Partners:
RLBP1
Retinaldehyde binding protein 1a.
    
 0.591
FAXDC2
Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family.
   
  
 0.578
RBP2
Retinol binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
     
 0.566
AKR1B1
Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 1.
   
 0.555
COX4I2
Cytochrome c oxidase subunit 4I2.
      
 0.480
RBP7
Retinol binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
     
 0.462
COX4I1
Cytochrome c oxidase subunit 4I1.
      
 0.459
LOC102350759
SEC14-like lipid binding 8.
    
 0.452
NEFL
Neurofilament light; Belongs to the intermediate filament family.
    
 
 0.442
TFAP2E
Transcription factor AP-2 epsilon.
    
 0.427
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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