STRINGSTRING
DHRS12 protein (Latimeria chalumnae) - STRING interaction network
"DHRS12" - Dehydrogenase/reductase (SDR family) member 12 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHRS12Dehydrogenase/reductase (SDR family) member 12 (325 aa)    
Predicted Functional Partners:
HADHA
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (766 aa)
   
  0.804
ACACA
acetyl-CoA carboxylase alpha (2312 aa)
   
 
  0.753
ACACB
acetyl-CoA carboxylase beta (2311 aa)
   
 
  0.753
ENSLACG00000014073
Uncharacterized protein (674 aa)
   
 
  0.640
ACSBG2
Uncharacterized protein (661 aa)
   
 
  0.640
ENSLACG00000006509
Uncharacterized protein (537 aa)
   
 
  0.640
ENSLACG00000005672
Uncharacterized protein (688 aa)
   
 
  0.640
OXCT1
3-oxoacid CoA transferase 1; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (530 aa)
       
  0.638
GNE
Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (742 aa)
   
   
  0.602
ACLY
ATP citrate lyase (978 aa)
   
 
  0.595
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
Server load: low (7%) [HD]