Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
P2RX6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (419 aa)    
Predicted Functional Partners:
DNAJB5
DnaJ heat shock protein family (Hsp40) member B5.
    
 
 0.956
PANX1
Pannexin; Structural component of the gap junctions and the hemichannels.
     
 0.870
CHEK2
Checkpoint kinase 2.
   
 0.789
CHEK1
Checkpoint kinase 1; Belongs to the protein kinase superfamily.
   
 0.747
YAF2
YY1 associated factor 2.
    
 0.671
RYBP
RING1 and YY1 binding protein.
    
 0.671
P2RX1
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
     
 0.643
SBK1
Serine/threonine-protein kinase SBK1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
   
  
 0.625
P2RX3
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
     
 0.620
DNAJB1
DnaJ heat shock protein family (Hsp40) member B1.
    
   0.611
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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