STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSDHLNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (340 aa)    
Predicted Functional Partners:
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.997
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
   
 0.993
CYP51A1
Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.
 
 
 0.987
SC5D
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 0.968
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
  
 
 0.954
DHCR7
7-dehydrocholesterol reductase.
   
 
 0.954
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
  
 
 0.944
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
  
 0.942
CH25H
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
   
 0.895
SQLE
SE domain-containing protein.
   
 
 0.891
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.