Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLC1A3Amino acid transporter. (441 aa)    
Predicted Functional Partners:
SLC7A5
Solute carrier family 7 member 5.
   
 
 0.775
SLC15A1
Solute carrier family 15 member 1.
   
 
 0.766
SLC3A1
Solute carrier family 3 member 1.
   
 
 0.752
GJA1
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
     
 0.686
SLC6A19
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
  
  
 0.676
SLC7A1
Solute carrier family 7 member 1.
   
 
 0.661
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
  
 0.649
SLC38A2
Solute carrier family 38 member 2.
      
 0.646
H3A9B7_LATCH
Uncharacterized protein.
   
 
 0.642
HMGCR
3-hydroxy-3-methylglutaryl coenzyme A reductase.
     
 0.635
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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