Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1185 aa)    
Predicted Functional Partners:
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.976
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
   
 0.962
PXN
Paxillin.
    
 0.961
TLN1
Talin 1.
    
 0.951
TLN2
Talin 2.
    
 0.951
LOC102349081
Integrin beta; Belongs to the integrin beta chain family.
   
 0.941
H3AM01_LATCH
Integrin beta; Belongs to the integrin beta chain family.
   
 0.926
SRC
Tyrosine-protein kinase.
    
 0.923
FN1
Fibronectin 1.
    
 0.916
ITGB7
Integrin beta; Belongs to the integrin beta chain family.
   
 0.908
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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