STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1185 aa)    
Predicted Functional Partners:
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
   
 0.944
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.943
LOC102349081
Integrin beta; Belongs to the integrin beta chain family.
   
 0.943
ACTN1
Uncharacterized protein.
     
 0.926
SRC
Tyrosine-protein kinase.
    
  0.907
PARVA
Parvin alpha.
   
 0.907
VCL
Vinculin.
   
 
 0.876
TLN1
Talin 1.
    
 0.868
TLN2
Talin 2.
    
 0.868
H3AM01_LATCH
Integrin beta; Belongs to the integrin beta chain family.
   
 0.862
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.