Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CASP10Caspase 10; Belongs to the peptidase C14A family. (539 aa)    
Predicted Functional Partners:
FADD
Fas associated via death domain.
   
 0.998
LOC102359774
Uncharacterized protein.
 
 
0.995
TRADD
Death domain-containing protein.
   
 0.995
LOC102349920
Uncharacterized protein.
   
 0.986
CASP6
Caspase 6; Belongs to the peptidase C14A family.
   
0.980
LOC102367521
Uncharacterized protein; Belongs to the peptidase C14A family.
  
0.978
CASP3
Caspase 3; Belongs to the peptidase C14A family.
  
0.977
CASP7
Caspase 7; Belongs to the peptidase C14A family.
   
0.976
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.959
MALT1
MALT1 paracaspase.
    
 0.953
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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