Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TTF1Transcription termination factor 1. (849 aa)    
Predicted Functional Partners:
CCDC59
Coiled-coil domain containing 59.
   
 
  0.971
MTERF1
Mitochondrial transcription termination factor 1.
      
 0.805
TTC27
Tetratricopeptide repeat domain 27.
   
  
 0.804
TAF1D
Uncharacterized protein.
   
 
 0.803
POLR1C
RNA polymerase I and III subunit C.
    
 0.801
POLR1E
RNA polymerase I subunit E.
    
 0.799
ECD
Ecdysoneless cell cycle regulator.
      
 0.792
TWISTNB
TWIST neighbor.
   
 0.774
CD3EAP
Uncharacterized protein.
    
 0.757
GPATCH4
G-patch domain containing 4.
    
   0.737
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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