Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NT5DC35'-nucleotidase domain containing 3. (472 aa)    
Predicted Functional Partners:
SYT17
Synaptotagmin 17.
      
 0.793
LOC102350904
5'-nucleotidase domain containing 2.
    
   0.743
NT5DC2
5'-nucleotidase domain containing 2.
    
   0.743
SAMM50
SAMM50 sorting and assembly machinery component.
      
 0.702
API5
Apoptosis inhibitor 5.
      
 0.696
MRPS18C
Mitochondrial ribosomal protein S18C; Belongs to the bacterial ribosomal protein bS18 family.
      
 0.591
NFYB
Nuclear transcription factor Y subunit beta.
      
 0.581
PIK3C2A
Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.
      
 0.577
ALDH4A1
Aldehyde dehydrogenase 4 family member A1; Belongs to the aldehyde dehydrogenase family.
    
   0.576
TIMM44
Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.
      
 0.573
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (16%) [HD]