STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IBA57Iron-sulfur cluster assembly factor IBA57. (314 aa)    
Predicted Functional Partners:
GCSH
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
     
 0.934
SHMT1
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
    
 0.925
SHMT2
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
    
 0.925
GLDC
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
     
 0.912
DHFR
Dihydrofolate reductase.
   
 
 0.911
LOC102346348
Zgc:153031; Belongs to the dihydrofolate reductase family.
   
 
 0.910
MTHFD2L
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like.
     
 0.892
MTHFD2
Uncharacterized protein.
     
 0.892
TYMS
Thymidylate synthetase.
    
  0.888
ISCA2
Iron-sulfur cluster assembly 2.
  
 
 0.840
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (20%) [HD]