STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOK7Docking protein 7. (565 aa)    
Predicted Functional Partners:
MUSK
Muscle associated receptor tyrosine kinase.
    
 0.951
H3A2R0_LATCH
Uncharacterized protein.
 
      0.881
AGRN
Agrin.
      
 0.699
RAPSN
Receptor associated protein of the synapse.
      
 0.699
COLQ
Collagen like tail subunit of asymmetric acetylcholinesterase.
      
 0.609
MICU1
Mitochondrial calcium uptake 1.
   
 0.580
CHRND
Cholinergic receptor nicotinic delta subunit.
      
 0.552
MCUB
Mitochondrial calcium uniporter dominant negative beta subunit.
     
 0.435
MCU
Mitochondrial calcium uniporter.
     
 0.435
SCN4A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
      
 0.431
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.