Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DOK7Docking protein 7. (565 aa)    
Predicted Functional Partners:
MUSK
Muscle associated receptor tyrosine kinase.
    
 0.994
RAPSN
Receptor associated protein of the synapse.
      
 0.925
H3A2R0_LATCH
Uncharacterized protein.
 
      0.881
AGRN
Agrin.
      
 0.846
COLQ
Collagen like tail subunit of asymmetric acetylcholinesterase.
      
 0.817
CHRNB3
Cholinergic receptor nicotinic beta 3 subunit.
      
 0.733
CHRND
Cholinergic receptor nicotinic delta subunit.
   
  
 0.692
SCN4A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
      
 0.596
SAMD11
Sterile alpha motif domain containing 11.
      
 0.591
CHRNA1
Cholinergic receptor nicotinic alpha 1 subunit.
      
 0.590
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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