Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2ZXH0_LATCHUncharacterized protein. (582 aa)    
Predicted Functional Partners:
CNOT1
CCR4-NOT transcription complex subunit 1.
    
 
 0.946
CNOT3
CCR4-NOT transcription complex subunit 3.
    
 
 0.871
H2ZVK6_LATCH
Uncharacterized protein; Belongs to the argonaute family.
    
 0.870
AGO4
Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.
    
 0.870
AGO1
Argonaute RISC component 1; Belongs to the argonaute family.
    
 0.870
CNOT9
CCR4-NOT transcription complex subunit 9.
    
 
 0.759
CNOT10
CCR4-NOT transcription complex subunit 10.
    
 
 0.726
CNOT8
CCR4-NOT transcription complex subunit 8.
    
 
 0.640
CNOT7
CCR4-NOT transcription complex subunit 7.
    
 
 0.640
UNC79
Unc-79 homolog, NALCN channel complex subunit.
      
 0.625
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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