STRINGSTRING
HELT protein (Latimeria chalumnae) - STRING interaction network
"HELT" - Helt bHLH transcription factor in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HELTHelt bHLH transcription factor (237 aa)    
Predicted Functional Partners:
STYK1
Serine/threonine/tyrosine kinase 1 (456 aa)
       
  0.647
NOTCH2
Notch 2 (2489 aa)
       
  0.576
ENSLACG00000003294
Neurogenic locus notch homolog protein 2 (1577 aa)
       
  0.576
ENSLACG00000016291
Uncharacterized protein (422 aa)
           
  0.558
ENSLACG00000015939
Probable G-protein coupled receptor 83 (438 aa)
           
  0.558
GPR83
G protein-coupled receptor 83 (424 aa)
           
  0.558
MEST
Mesoderm specific transcript homolog (mouse) (338 aa)
           
  0.557
AVEN
Apoptosis, caspase activation inhibitor (348 aa)
           
  0.553
NOTCH1
Notch 1 (2494 aa)
       
  0.533
ENSLACG00000012848
Uncharacterized protein (2519 aa)
       
  0.533
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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