Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC102367471Uncharacterized protein; Belongs to the cyclin family. (292 aa)    
Predicted Functional Partners:
RB1
Uncharacterized protein.
    
 0.975
RBL2
RB transcriptional corepressor like 2.
    
 0.970
RBL1
RB transcriptional corepressor like 1.
    
 0.970
LOC102356560
ANK_REP_REGION domain-containing protein.
    
 0.963
CDKN2C
Cyclin dependent kinase inhibitor 2C.
    
 0.960
CDKN1A
Cyclin dependent kinase inhibitor 1A.
   
 0.960
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.957
CDK6
Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.956
CDK4
Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.956
LOC102366718
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.956
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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