BBS4 protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

BBS4

Bardet-Biedl syndrome 4. (537 aa)

Predicted Functional Partners:

BBS7

0.999

H3A6Z7_LATCH

0.999

BBS9

0.999

BBS2

0.999

TTC8

0.992

LZTFL1

0.990

PCM1

0.986

BBS9-2

0.967

BBS5

0.966

KLHL41

0.966

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS2	BBS4	ENSLACP00000017026	ENSLACP00000002102	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 4.	0.999
BBS2	BBS5	ENSLACP00000017026	ENSLACP00000013671	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 5 protein homolog; Required for ciliogenesis; Belongs to the BBS5 family.	0.988
BBS2	BBS7	ENSLACP00000017026	ENSLACP00000002676	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.999
BBS2	BBS9	ENSLACP00000017026	ENSLACP00000007483	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 9.	0.999
BBS2	BBS9-2	ENSLACP00000017026	ENSLACP00000022559	Bardet-Biedl syndrome 2 protein homolog.	PHTB1_C domain-containing protein.	0.985
BBS2	H3A6Z7_LATCH	ENSLACP00000017026	ENSLACP00000005418	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 1.	0.999
BBS2	KLHL41	ENSLACP00000017026	ENSLACP00000013868	Bardet-Biedl syndrome 2 protein homolog.	Kelch like family member 41.	0.976
BBS2	LZTFL1	ENSLACP00000017026	ENSLACP00000001505	Bardet-Biedl syndrome 2 protein homolog.	Leucine zipper transcription factor like 1.	0.995
BBS2	PCM1	ENSLACP00000017026	ENSLACP00000023595	Bardet-Biedl syndrome 2 protein homolog.	Pericentriolar material 1.	0.444
BBS2	TTC8	ENSLACP00000017026	ENSLACP00000022744	Bardet-Biedl syndrome 2 protein homolog.	Tetratricopeptide repeat domain 8.	0.999
BBS4	BBS2	ENSLACP00000002102	ENSLACP00000017026	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 2 protein homolog.	0.999
BBS4	BBS5	ENSLACP00000002102	ENSLACP00000013671	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 5 protein homolog; Required for ciliogenesis; Belongs to the BBS5 family.	0.966
BBS4	BBS7	ENSLACP00000002102	ENSLACP00000002676	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.999
BBS4	BBS9	ENSLACP00000002102	ENSLACP00000007483	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 9.	0.999
BBS4	BBS9-2	ENSLACP00000002102	ENSLACP00000022559	Bardet-Biedl syndrome 4.	PHTB1_C domain-containing protein.	0.967
BBS4	H3A6Z7_LATCH	ENSLACP00000002102	ENSLACP00000005418	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 1.	0.999
BBS4	KLHL41	ENSLACP00000002102	ENSLACP00000013868	Bardet-Biedl syndrome 4.	Kelch like family member 41.	0.966
BBS4	LZTFL1	ENSLACP00000002102	ENSLACP00000001505	Bardet-Biedl syndrome 4.	Leucine zipper transcription factor like 1.	0.990
BBS4	PCM1	ENSLACP00000002102	ENSLACP00000023595	Bardet-Biedl syndrome 4.	Pericentriolar material 1.	0.986
BBS4	TTC8	ENSLACP00000002102	ENSLACP00000022744	Bardet-Biedl syndrome 4.	Tetratricopeptide repeat domain 8.	0.992