KLHL35 protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

KLHL35

Kelch like family member 35. (600 aa)

Predicted Functional Partners:

CUL3

0.937

KLHL28

0.756

CREBRF

0.633

H3A6Z7_LATCH

0.606

BBS4

0.603

TTC8

0.563

KBTBD4

0.534

BBS7

0.528

BBS9

0.509

BBS9-2

0.509

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS4	BBS7	ENSLACP00000002102	ENSLACP00000002676	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.999
BBS4	BBS9	ENSLACP00000002102	ENSLACP00000007483	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 9.	0.999
BBS4	BBS9-2	ENSLACP00000002102	ENSLACP00000022559	Bardet-Biedl syndrome 4.	PHTB1_C domain-containing protein.	0.967
BBS4	H3A6Z7_LATCH	ENSLACP00000002102	ENSLACP00000005418	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 1.	0.999
BBS4	KLHL28	ENSLACP00000002102	ENSLACP00000001002	Bardet-Biedl syndrome 4.	Kelch like family member 28.	0.603
BBS4	KLHL35	ENSLACP00000002102	ENSLACP00000002103	Bardet-Biedl syndrome 4.	Kelch like family member 35.	0.603
BBS4	TTC8	ENSLACP00000002102	ENSLACP00000022744	Bardet-Biedl syndrome 4.	Tetratricopeptide repeat domain 8.	0.992
BBS7	BBS4	ENSLACP00000002676	ENSLACP00000002102	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Bardet-Biedl syndrome 4.	0.999
BBS7	BBS9	ENSLACP00000002676	ENSLACP00000007483	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Bardet-Biedl syndrome 9.	0.999
BBS7	BBS9-2	ENSLACP00000002676	ENSLACP00000022559	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	PHTB1_C domain-containing protein.	0.984
BBS7	H3A6Z7_LATCH	ENSLACP00000002676	ENSLACP00000005418	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Bardet-Biedl syndrome 1.	0.999
BBS7	KBTBD4	ENSLACP00000002676	ENSLACP00000021621	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Kelch repeat and BTB domain containing 4.	0.430
BBS7	KLHL28	ENSLACP00000002676	ENSLACP00000001002	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Kelch like family member 28.	0.528
BBS7	KLHL35	ENSLACP00000002676	ENSLACP00000002103	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Kelch like family member 35.	0.528
BBS7	TTC8	ENSLACP00000002676	ENSLACP00000022744	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Tetratricopeptide repeat domain 8.	0.999
BBS9	BBS4	ENSLACP00000007483	ENSLACP00000002102	Bardet-Biedl syndrome 9.	Bardet-Biedl syndrome 4.	0.999
BBS9	BBS7	ENSLACP00000007483	ENSLACP00000002676	Bardet-Biedl syndrome 9.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.999
BBS9	BBS9-2	ENSLACP00000007483	ENSLACP00000022559	Bardet-Biedl syndrome 9.	PHTB1_C domain-containing protein.	0.970
BBS9	H3A6Z7_LATCH	ENSLACP00000007483	ENSLACP00000005418	Bardet-Biedl syndrome 9.	Bardet-Biedl syndrome 1.	0.999
BBS9	KLHL28	ENSLACP00000007483	ENSLACP00000001002	Bardet-Biedl syndrome 9.	Kelch like family member 28.	0.509