Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM222AFamily with sequence similarity 222 member A. (442 aa)    
Predicted Functional Partners:
MEIS1
Meis homeobox 1.
    
   0.756
MAB21L2
Mab-21-like 2.
    
   0.756
MAB21L1
Mab-21 like 1.
    
   0.756
MEIS2
Meis homeobox 2.
    
   0.756
LOC102353948
Nemo-like kinase, type 1.
    
   0.644
NLK
Mitogen-activated protein kinase.
    
   0.644
ZNFX1
Zinc finger NFX1-type containing 1.
      
 0.641
MBIP
MAP3K12 binding inhibitory protein 1.
      
 0.592
ANKRD13D
Ankyrin repeat domain 13D.
      
 0.566
H3AM53_LATCH
PBC domain-containing protein.
    
   0.525
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (18%) [HD]