Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2ZXM4_LATCHEGF-like domain-containing protein. (580 aa)    
Predicted Functional Partners:
H3ABR4_LATCH
Uncharacterized protein.
 
      0.895
LOC102367052
Uncharacterized protein.
 
   
0.729
LDLRAP1
Low density lipoprotein receptor adaptor protein 1b.
    
 0.637
AXIN1
Axin 1.
    
 0.595
AXIN2
Axin 2.
    
 0.595
WNT1
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.594
PCSK9
Proprotein convertase subtilisin/kexin type 9.
    
 0.592
DAB1
DAB adaptor protein 1.
    
 0.581
H3A5Z1_LATCH
Uncharacterized protein.
 
     
0.580
ITSN2
Intersectin 2.
    
 0.571
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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