Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC102358615Uncharacterized protein. (553 aa)    
Predicted Functional Partners:
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.992
IL1RAP
Interleukin 1 receptor accessory protein.
   
0.991
IRAK1
Interleukin 1 receptor associated kinase 1.
    
 0.901
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.889
IRAK4
Interleukin 1 receptor associated kinase 4.
    
 0.812
TOLLIP
Toll interacting protein.
    
 0.774
H3AUI4_LATCH
Uncharacterized protein.
    
 0.766
IRAK3
Interleukin 1 receptor associated kinase 3.
   
 0.529
IL18
Uncharacterized protein.
     
 0.492
H3B449_LATCH
Interleukin-1.
     
  0.490
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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