Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF167Ring finger protein 167. (383 aa)    
Predicted Functional Partners:
AP3D1
Adaptor related protein complex 3 subunit delta 1.
    
   0.684
CD63
Tetraspanin.
   
 
 0.632
FZD6
Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 
 0.591
HSF2BP
Heat shock transcription factor 2 binding protein.
      
 0.589
TMEM183A
Transmembrane protein 183A.
      
 0.589
NUS1
NUS1 dehydrodolichyl diphosphate synthase subunit.
      
 0.587
ARPIN
Uncharacterized protein.
    
 
 0.574
AP3S1
Adaptor related protein complex 3 subunit sigma 1.
    
 
 0.574
UBE2N
Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.565
CLCN7
Chloride channel protein.
    
   0.564
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (20%) [HD]