Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (846 aa)    
Predicted Functional Partners:
POLR2G
RNA polymerase II subunit G.
    
 0.994
POLR2C
RNA polymerase II subunit C.
    
 0.992
GTF2F1
Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.
   
 0.992
POLR2B
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.986
CDK9
Cyclin dependent kinase 9; Belongs to the protein kinase superfamily.
    
 0.985
H3A8J5_LATCH
Uncharacterized protein.
    
 0.978
POLR2A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.978
RPRD1B
Regulation of nuclear pre-mRNA domain containing 1B.
    
 
 0.970
POLR2D
RNA polymerase II subunit D.
    
 0.969
SUPT6H
Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.
     
 0.964
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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