Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
SNRPD1Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (121 aa)    
Predicted Functional Partners:
H2ZZC6_LATCH
Sm domain-containing protein.
   
 0.999
SNRPD2
Small nuclear ribonucleoprotein Sm D2.
   
 0.999
SNRPB
Small nuclear ribonucleoprotein-associated protein.
   
 0.999
SNRPE
Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
   
 0.999
SNRPD3
Small nuclear ribonucleoprotein Sm D3.
   
0.999
SNRPG
Small nuclear ribonucleoprotein G.
   
 0.999
SNRPC
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]
   
 0.994
SNRNP70
Small nuclear ribonucleoprotein U1 subunit 70.
   
 0.993
SNRPA1
Small nuclear ribonucleoprotein polypeptide A.
   
 0.993
SF3A2
Splicing factor 3a subunit 2.
   
 0.992
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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