Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MTMR3Myotubularin related protein 3. (1222 aa)    
Predicted Functional Partners:
MTMR4
Myotubularin related protein 4.
  
 
0.994
PIP4P2
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
 
   
 0.929
PIP4K2B
Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.
    
 0.922
PIP4K2A
Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha.
    
 0.922
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
     
 0.920
PIKFYVE
Phosphoinositide kinase, FYVE-type zinc finger containing.
     
0.920
INPP4A
Inositol polyphosphate-4-phosphatase type I A.
     
 0.911
FIG4
FIG4 phosphoinositide 5-phosphatase.
     
 0.911
PIP4P1
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
     
 0.910
INPP4B
Inositol polyphosphate-4-phosphatase type II B.
     
 0.908
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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