Groups of genes that are frequently observed in each other's genomic neighborhood.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Carbonic anhydrase (253 aa)
Predicted Functional Partners:
Purine-rich element binding protein A (307 aa)
XK-related protein; X-linked Kx blood group (445 aa)
Apolipoprotein M (194 aa)
Complement component 4 (1606 aa)
Phosphoglycerate dehydrogenase (522 aa)
Uncharacterized protein; Solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 (161 aa)
Sodium/hydrogen exchanger; Solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3; Belongs to the monovalent cation-proton antiporter 1 (CPA1) transporter (TC 2.A.36) family (765 aa)
Serpin family C member 1; Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family (485 aa)
Uncharacterized protein; Kininogen 1 (497 aa)
Solute carrier family 9 (sodium/hydrogen exchanger), member 2; Belongs to the monovalent cation-proton antiporter 1 (CPA1) transporter (TC 2.A.36) family (593 aa)
Your Current Organism:
NCBI taxonomy Id: 7897 Other names: L. chalumnae, Latimeria chalumnae, coelacanth