H2ZXV1_LATCH protein (Latimeria chalumnae) - STRING interaction network

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Score

H2ZXV1_LATCH

Endo/exonuclease/phosphatase domain-containing protein. (379 aa)

Predicted Functional Partners:

NTHL1

0.518

PCNA

0.504

MUTYH

0.437

UNG

0.421

H3ALV1_LATCH

0.408

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H2ZXV1_LATCH	H3ALV1_LATCH	ENSLACP00000002222	ENSLACP00000010622	Endo/exonuclease/phosphatase domain-containing protein.	Uncharacterized protein.	0.408
H2ZXV1_LATCH	MUTYH	ENSLACP00000002222	ENSLACP00000023303	Endo/exonuclease/phosphatase domain-containing protein.	Uncharacterized protein.	0.437
H2ZXV1_LATCH	NTHL1	ENSLACP00000002222	ENSLACP00000001243	Endo/exonuclease/phosphatase domain-containing protein.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	0.518
H2ZXV1_LATCH	PCNA	ENSLACP00000002222	ENSLACP00000006575	Endo/exonuclease/phosphatase domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.504
H2ZXV1_LATCH	UNG	ENSLACP00000002222	ENSLACP00000014193	Endo/exonuclease/phosphatase domain-containing protein.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.421
H3ALV1_LATCH	H2ZXV1_LATCH	ENSLACP00000010622	ENSLACP00000002222	Uncharacterized protein.	Endo/exonuclease/phosphatase domain-containing protein.	0.408
H3ALV1_LATCH	NTHL1	ENSLACP00000010622	ENSLACP00000001243	Uncharacterized protein.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	0.615
H3ALV1_LATCH	PCNA	ENSLACP00000010622	ENSLACP00000006575	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.998
H3ALV1_LATCH	UNG	ENSLACP00000010622	ENSLACP00000014193	Uncharacterized protein.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.639
MUTYH	H2ZXV1_LATCH	ENSLACP00000023303	ENSLACP00000002222	Uncharacterized protein.	Endo/exonuclease/phosphatase domain-containing protein.	0.437
MUTYH	NTHL1	ENSLACP00000023303	ENSLACP00000001243	Uncharacterized protein.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	0.711
MUTYH	PCNA	ENSLACP00000023303	ENSLACP00000006575	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.886
MUTYH	UNG	ENSLACP00000023303	ENSLACP00000014193	Uncharacterized protein.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.790
NTHL1	H2ZXV1_LATCH	ENSLACP00000001243	ENSLACP00000002222	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	Endo/exonuclease/phosphatase domain-containing protein.	0.518
NTHL1	H3ALV1_LATCH	ENSLACP00000001243	ENSLACP00000010622	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	Uncharacterized protein.	0.615
NTHL1	MUTYH	ENSLACP00000001243	ENSLACP00000023303	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	Uncharacterized protein.	0.711
NTHL1	PCNA	ENSLACP00000001243	ENSLACP00000006575	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.640
NTHL1	UNG	ENSLACP00000001243	ENSLACP00000014193	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.653
PCNA	H2ZXV1_LATCH	ENSLACP00000006575	ENSLACP00000002222	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Endo/exonuclease/phosphatase domain-containing protein.	0.504
PCNA	H3ALV1_LATCH	ENSLACP00000006575	ENSLACP00000010622	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.998