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STRINGSTRING
DRD3 protein (Latimeria chalumnae) - STRING interaction network
"DRD3" - Dopamine receptor D3 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family (443 aa)    
Predicted Functional Partners:
SIGIRR
Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (417 aa)
           
  0.793
SLC6A3
Transporter; Solute carrier family 6 (neurotransmitter transporter), member 3; Belongs to the sodium-neurotransmitter symporter (SNF) (TC 2.A.22) family (624 aa)
     
 
  0.778
GRK4
G protein-coupled receptor kinase 4; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily (510 aa)
       
 
  0.678
BDNF
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it (254 aa)
           
  0.678
PALMD
Palmdelphin (561 aa)
           
  0.672
GMIP
GEM interacting protein (962 aa)
     
   
  0.653
VWA3A
Von Willebrand factor A domain containing 3A (1175 aa)
           
  0.646
HS1BP3
HCLS1 binding protein 3 (186 aa)
           
  0.639
EPHA6
Uncharacterized protein (161 aa)
       
 
  0.637
DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains; Belongs to the DAD/OST2 family (113 aa)
           
  0.630
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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