STRINGSTRING
RPE65 protein (Latimeria chalumnae) - STRING interaction network
"RPE65" - Retinal pigment epithelium-specific protein 65kDa in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPE65Retinal pigment epithelium-specific protein 65kDa (533 aa)    
Predicted Functional Partners:
RDH10
Retinol dehydrogenase 10 (all-trans) (348 aa)
     
 
  0.913
DGAT1
Diacylglycerol O-acyltransferase 1 (422 aa)
     
 
    0.903
PNPLA4
Patatin-like phospholipase domain containing 4 (166 aa)
         
    0.900
TULP1
Tubby like protein 1 (530 aa)
           
  0.637
rh2
Blue-sensitive opsin (355 aa)
     
   
  0.598
RHO
Rhodopsin (355 aa)
     
   
  0.596
RLBP1
Retinaldehyde binding protein 1 (174 aa)
     
   
  0.582
PDE6C
Phosphodiesterase 6C, cGMP-specific, cone, alpha prime (838 aa)
     
   
  0.496
GRK1
G protein-coupled receptor kinase 1; Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination (566 aa)
     
   
  0.485
ENSLACG00000011283
Protein-serine/threonine kinase (563 aa)
     
   
  0.485
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
Server load: low (7%) [HD]