Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC102357379Sulfatase domain-containing protein. (174 aa)    
Predicted Functional Partners:
H3AB56_LATCH
Sulfatase domain-containing protein.
 
     0.950
STS
Steroid sulfatase.
 
  
  0.913
SUMF1
Sulfatase modifying factor 1.
  
 0.864
GALNS
Galactosamine (N-acetyl)-6-sulfatase.
   
 0.826
TRIP13
Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family.
    
  0.743
MED14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.717
ARSK
Arylsulfatase family member K.
  
 
 0.684
SUMF2
Sulfatase modifying factor 2.
  
 0.683
SFTPB
Uncharacterized protein.
     
 0.675
PSAP
Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
     
 0.675
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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