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STRINGSTRING
ENSLACG00000002022 protein (Latimeria chalumnae) - STRING interaction network
"ENSLACG00000002022" - L-selectin in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
ENSLACG00000002022L-selectin; Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia (385 aa)    
Predicted Functional Partners:
AP2M1
Adaptor-related protein complex 2, mu 1 subunit, a; Belongs to the adaptor complexes medium subunit family (434 aa)
       
      0.782
CD44
Uncharacterized protein; CD44 molecule (Indian blood group) (405 aa)
       
 
  0.609
TNF
Uncharacterized protein (230 aa)
       
 
  0.515
ENSLACG00000000241
Uncharacterized protein (143 aa)
       
 
  0.515
VCAM1
Vascular cell adhesion molecule 1 (733 aa)
     
   
  0.513
GLG1
Golgi glycoprotein 1 (222 aa)
       
 
  0.500
VWF
Von Willebrand factor (2833 aa)
     
   
  0.486
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (618 aa)
     
 
  0.457
WDTC1
WD and tetratricopeptide repeats 1 (646 aa)
           
  0.445
SNX17
Sorting nexin 17 (455 aa)
       
 
  0.443
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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