Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H2ZXZ3_LATCHL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (385 aa)    
Predicted Functional Partners:
H3AUC6_LATCH
Link domain-containing protein.
    
 0.823
CD63
Tetraspanin.
     
 0.676
CD34
Uncharacterized protein.
    
 0.667
SNX17
Sorting nexin 17.
    
 
 0.576
LOC102358289
Uncharacterized protein.
   
 0.570
CD36
CD36 molecule; Belongs to the CD36 family.
   
 
 0.551
VCAM1
Vascular cell adhesion molecule 1.
   
 
 0.541
H3AM01_LATCH
Integrin beta; Belongs to the integrin beta chain family.
   
 
 0.496
CCR7
C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.483
ITGA8
Integrin subunit alpha 8; Belongs to the integrin alpha chain family.
   
 
 0.477
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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