Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EEF2KEukaryotic elongation factor 2 kinase. (512 aa)    
Predicted Functional Partners:
FBXW11
F-box and WD repeat domain containing 11.
    
 
 0.953
LOC102366825
Tr-type G domain-containing protein.
   
 
 0.931
H3A8H2_LATCH
Uncharacterized protein.
    
 
 0.930
EEF2
Eukaryotic translation elongation factor 2, like 2.
   
 
 0.909
EPB41
Erythrocyte membrane protein band 4.1.
    
   0.895
LOC102361574
Non-specific serine/threonine protein kinase.
    
 0.845
RPS6KB1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.845
DIDO1
Death inducer-obliterator 1.
      
 0.790
FKBP6
Peptidylprolyl isomerase.
    
   0.686
MAT2B
Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.
   
 
 0.682
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (14%) [HD]