Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OSBPL10Oxysterol-binding protein; Belongs to the OSBP family. (567 aa)    
Predicted Functional Partners:
OSBPL9
Oxysterol-binding protein; Belongs to the OSBP family.
   
   0.783
VAPB
VAMP associated protein B and C.
   
 
 0.783
VAPA
VAMP associated protein A.
   
 
 0.765
LARS2
Leucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
  
 0.633
RHOH
Ras homolog family member H.
    
 0.632
DPP3
Dipeptidyl peptidase 3; Belongs to the peptidase M49 family.
    
 
 0.621
NIPSNAP2
Nipsnap homolog 2.
   
  0.618
NIPSNAP1
Nipsnap homolog 1.
   
  0.618
PGAM5
PGAM family member 5, mitochondrial serine/threonine protein phosphatase.
    
   0.617
UQCRC1
Ubiquinol-cytochrome c reductase core protein 1.
      
 0.613
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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