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AMD1 protein (Latimeria chalumnae) - STRING interaction network
"AMD1" - S-adenosylmethionine decarboxylase proenzyme in Latimeria chalumnae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMD1S-adenosylmethionine decarboxylase proenzyme; Adenosylmethionine decarboxylase 1 (333 aa)    
Predicted Functional Partners:
SMS
Spermine synthase (311 aa)
   
 
  0.978
MAT2A
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP (391 aa)
     
 
  0.953
MAT1A
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP (391 aa)
     
 
  0.953
MAT2B
Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L- methionine (341 aa)
     
 
  0.913
DNMT1
DNA (cytosine-5-)-methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family (1273 aa)
         
  0.902
GART
Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the C-terminal section; belongs to the GART family (1031 aa)
     
   
  0.900
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha (658 aa)
         
    0.900
ODC1
Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family (464 aa)
 
 
 
  0.890
SRM
Spermidine synthase; Belongs to the spermidine/spermine synthase family (290 aa)
   
   
  0.848
ARG2
Arginase 2 (363 aa)
         
  0.789
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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