Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
DEGS2Delta 4-desaturase, sphingolipid 2. (322 aa)    
Predicted Functional Partners:
ACER3
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
   
 
 0.962
GALC
Galactosylceramidase.
     
 0.956
KDSR
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.953
CERS5
Ceramide synthase 5.
   
 0.949
CERS1
Ceramide synthase 1.
   
 0.945
CERS2
Ceramide synthase 2.
   
 0.945
CERS3
Ceramide synthase 3.
   
 0.945
SAMD8
Sterile alpha motif domain containing 8.
   
 
 0.941
ASAH1
N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family.
     
 0.941
SGPP1
Sphingosine-1-phosphate phosphatase 1.
     
 0.941
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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