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ADSSL1 protein (Latimeria chalumnae) - STRING interaction network
"ADSSL1" - Adenylosuccinate synthase like 1 in Latimeria chalumnae
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ADSSL1Adenylosuccinate synthase like 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP (449 aa)    
Predicted Functional Partners:
CAD
Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (2203 aa)
   
 
  0.990
ADSL
Adenylosuccinate lyase (500 aa)
 
 
  0.986
IMPDH1
IMP (inosine 5’-monophosphate) dehydrogenase 1 (515 aa)
   
 
  0.980
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (594 aa)
   
  0.976
GART
Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (1031 aa)
   
  0.973
HPRT1
Hypoxanthine phosphoribosyltransferase 1 (180 aa)
   
 
  0.971
ENSLACG00000005452
Uncharacterized protein (214 aa)
   
 
  0.971
ITPA
Inosine triphosphatase (nucleoside triphosphate pyrophosphatase); Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2’-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5’-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions (192 aa)
   
  0.970
GMPR
Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (345 aa)
   
 
  0.961
GMPR2
Guanosine monophosphate reductase 2; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (350 aa)
   
 
  0.961
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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