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STRINGSTRING
REST protein (Latimeria chalumnae) - STRING interaction network
"REST" - Uncharacterized protein in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RESTUncharacterized protein; RE1-silencing transcription factor (324 aa)    
Predicted Functional Partners:
SIN3B
SIN3 transcription regulator family member B (1150 aa)
     
 
  0.917
SIN3A
SIN3 transcription regulator family member A (1124 aa)
     
 
  0.901
RCOR1
Uncharacterized protein; REST corepressor 1 (272 aa)
     
 
  0.889
HTT
Huntingtin (3125 aa)
     
 
  0.743
NPC2
NPC intracellular cholesterol transporter 2; Niemann-Pick disease, type C2 (148 aa)
           
  0.655
PTBP1
Polypyrimidine tract binding protein 1 (560 aa)
     
   
  0.644
CTDSP2
CTD small phosphatase 2; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 (271 aa)
     
 
  0.636
BDNF
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it (254 aa)
           
  0.635
SMARCB1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 (384 aa)
       
 
  0.613
ACTL6A
Actin-like 6A; Belongs to the actin family (429 aa)
     
 
  0.594
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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