Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
LOC102349251Rap-GAP domain-containing protein. (647 aa)    
Predicted Functional Partners:
RAP1B
RAP1B, member of RAS oncogene family.
    
 0.810
RAP1A
RAP1A, member of RAS oncogene family b.
    
 0.810
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.
    
  0.664
YWHAZ
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
  0.612
LOC102362951
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
    
  0.566
PRKACB
Uncharacterized protein; Belongs to the protein kinase superfamily.
    
  0.566
RAPGEF3
Ras-GEF domain-containing protein.
   
 0.558
DIRAS1
DIRAS family GTPase 1.
    
 0.528
DIRAS2
DIRAS family GTPase 2.
    
 0.528
RAP2C
Uncharacterized protein.
    
 0.528
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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